So if youre taking Zetia with a statin drug, you may need to avoid eating grapefruit or drinking grapefruit juice during your treatment. Some people may develop mild or serious side effects during Zetia treatment. The causes of POTS are unknown, but the problem is thought to lie in the communication breakdown between the brain and the cardiovascular system. If the side effects seem life threatening or if you think youre having a medical emergency, immediately call 911 or your local emergency number. Dizziness is a rare side effect of taking Zetia. But if you have any symptoms that are ongoing or that bother you, talk with your doctor or pharmacist. High cholesterol occurs when you have more cholesterol in your blood than your body needs. Zetia is meant to be used in combination with a diet thats low in saturated fat and cholesterol. They are caused by deficiencies in enzymes involved in the synthesis of heme. Its primary metabolic pathway is via hepatic glucuronic conjunction. This date is typically 1 year from the date they dispensed the medication. Its not clear if CoQ10 prevents muscle-related side effects when Zetia is taken with a statin, but it might help. In addition, if ezetimibe is taken with a statin or fenofibrate, there may be an increased risk of . Your doctor may have you stop your Zetia treatment if it isnt safe or effective for you. This is because large meals can cause blood to pool excessively in the abdomen. If you and your doctor decide that Zetia treatment isnt right for you, you simply wont take any more doses. For more information, see the How Zetia works section below. Serious side effects from Zetia arent common, but they can occur. When you get Zetia from the pharmacy, the pharmacist will add an expiration date to the label on the bottle. Ezetimibe may cause side effects. Ezetimibe may be used alone or with other drugs (such as "statins" or . Forget HDL and LDL. Yes, there are a few. Homozygous sitosterolemia is a genetic condition caused by a mutation (change) in the genes that control how plant sterols are cleared from your body. (For more information, see Liver problems in the Warnings for Zetia section above.). Bethenny Frankel is opening up about her health issue, explaining to her Instagram followers about her battle with postural orthostatic tachycardia syndrome (POTS) after receiving comments about . For instance, some interactions can interfere with how well a drug works. It may take about 2 weeks for your cholesterol levels to improve after you start taking Zetia. The insurance company will review the prior authorization request and decide if the drug will be covered. Its also not known if the drug is safe to take while breastfeeding or whether the drug passes into breast milk. It is created by eHealthMe based on reports of 45,364 people who have side effects when taking Zetia from the FDA, and is updated regularly. Pots or postural tachycardia syndrome is, also known as postural orthostatic tachycardia syndrome, is a condition that affects the flow of blood in the heart and brain. Your body uses cholesterol to make some vitamins, hormones, and fluids that help you digest food. Cholesterol can also be found in foods such as eggs, cheese, and meat. Here are a few questions to get your discussion started with your doctor: To get information on different conditions and tips for improving your health, subscribe to any of Healthlines newsletters. It also isnt known how many adults and children experienced joint pain in clinical studies of Zetia used to treat other conditions. Phase IV trials are used to detect adverse drug . Dr. said Zetia was different and would not cause these side effects, so I agreed to try it. In clinical studies that lasted 8 weeks, Zetia was compared with a placebo (a treatment with no active drug). Clinical studies have shown Zetia to be effective for treating homozygous familial hypercholesterolemia when used with atorvastatin or simvastatin. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. Learn more about some of the side effects that Zetia may cause. Zetia is primarily cleared from the body through fecal excretion. Phil Fischer, M.D., medical director of Mayo Clinic's children's hospital and a POTS specialist, led . They may also check you for signs of muscle breakdown or kidney damage. Here are answers to some frequently asked questions about Zetia. Within 4 to 12 hours of oral administration, a single 10-mg dose of Zetia reaches peak plasma concentrations of 3.4 to 5.5 ng/mL. Statins are cholesterol drugs that may be taken with Zetia. When taken together, it should be administered at least 2 hours before or 4 hours after a bile acid sequestrant. These lists contain up to 10 of the most common mild side effects that can occur with Zetia, with Lipitor, or with both drugs (when taken individually). Is the ketogenic diet right for autoimmune conditions? POTS is commonly associated with low levels of fluid. MS: Can the Mediterranean diet help preserve cognitive health? There arent any herbs or supplements that have been specifically reported to interact with Zetia. Healthline Media does not provide medical advice, diagnosis, or treatment. Zinnia elegans 'Benary's Giant Golden Yellow'. Do my other medications increase my risk of side effects with Zetia? 4. The Food and Drug Administration (FDA) approves prescription drugs such as Zetia to treat certain conditions. If you have a history of heavy alcohol use and are taking Zetia with a statin drug, you may have a higher risk of side effects. Ask your doctor what other medications are better options for you. Absorption isnt affected by food. Total cholesterol consists of: High cholesterol occurs when you have more cholesterol in your blood than your body needs. If you have any questions about eating certain foods while taking Zetia, talk with your doctor. Grapefruit can prevent the breakdown of statins in your body, which can raise your levels of these drugs and increase your risk of side effects. Zetia may cause mild side effects other than the ones listed above. Some may be a better fit for you than others. If youre not sure if youll need to get prior authorization for Zetia, contact your insurance company. Welchol is a prescription drug used to treat type 2 diabetes and high cholesterol. Lipitor is available in a generic form called atorvastatin. Bethenny Frankel is opening up about her health issue, explaining to her Instagram followers about her battle with postural orthostatic tachycardia syndrome (POTS) after receiving comments about the change in her physical appearance. However, you may need to avoid grapefruit if you take Zetia with a statin, another type of cholesterol medication. Lipitor and Zetia belong to different drug classes. For some drugs, doing so may lead to unwanted side effects or overdose. Zetia and Lipitor have some similar side effects and others that vary. For more information, see the Precautions section below. Read more about how inherited high cholesterol affects life expectancy and what makes it different from regular hypercholesterolemia. Statins are another type of medication used to lower cholesterol. Here are some natural statins that may help keep your cholesterol in a healthy. Statin drugs arent safe to use during pregnancy. Tell them about all prescription, over-the-counter, and other drugs you take. Effects of coenzyme Q10 on statin-induced myopathy: An updated meta-analysis of randomized controlled trials. Zetia is contraindicated under the following conditions: Zetia tablets should be stored at a room temperature of 77F (25C) in a tightly sealed container away from light. Nausea/Vomiting. Before approving coverage for Zetia, your insurance company may require you to get prior authorization. For more information on these side effects, see Side effect details below. * Sex and gender exist on spectrums. Learn about side effects, costs. These symptoms could be life threatening and require immediate medical care. Zetias effect on cardiovascular morbidity and mortality isnt known. If your doctor has prescribed Zetia and youre interested in using ezetimibe instead, talk with your doctor. Zetia contains the active drug ezetimibe. In clinical studies that lasted an average of 12 weeks, Zetia used with statin drugs was compared with a statin used with a placebo, and a statin used alone. Lipitor is part of the statin drug class. For mixed high cholesterol, Zetia is FDA-approved to decrease levels of: For this purpose, Zetia is used with a low-cholesterol diet and is taken with other drugs. (For more information on the specific conditions Zetia can treat, see the Zetia uses section.). POTS is a form of "autonomic dysregulation" (a nervous system disorder) in which your heart rate spikes upon standing (among other symptoms). If youre currently taking cyclosporine, talk with your doctor about whether its safe for you to take Zetia. Zetia isnt a statin drug. As patients we need to be constantly wary because it is increasingly clear that the pharmas have abrogated their responsibility on our behalf. For most people, CoQ10 isnt a harmful or dangerous supplement. However, you may still experience muscle problems if you use Zetia alone. Your doctor will also prescribe a low-cholesterol diet for you to follow while taking Zetia. Leqvio is a prescription drug used to lower cholesterol. If you have liver problems, your liver may not work properly to remove medications such as Zetia from your body. If you have questions about drug interactions that may affect you, ask your doctor or pharmacist. Then you can share this information with your doctor. Zetia hasnt been studied in certain types of dyslipidemia, including Frederickson types I, III, IV, and V. Zetia is taken orally with or without food. They may be able to suggest ways to relieve this side effect. Zetia is FDA-approved to lower your total cholesterol level, and triglycerides are one part of your total cholesterol level. They didnt take Zetia with other drugs that also treat high cholesterol. upper respiratory tract infection, including the common cold. If your liver function tests show increased liver enzymes called transaminases while youre using Zetia with a statin drug, your doctor may stop your treatment. Fatigue. The heartbeat increases with a feeling of the heart fluttering. Uses. To determine whether you have high cholesterol, your doctor will do a blood test called a lipid panel. It isnt safe to eat grapefruit or drink grapefruit juice while using statins. Energy Drinks, such as Red Bull, should be avoided in those with POTS. Symptoms of atherosclerosis may include confusion, fatigue (lack of energy), trouble breathing, or pain in your chest, arms, or legs. Talk with your doctor or pharmacist if you have trouble swallowing Zetia tablets. This may be caused by genetics, smoking, not getting enough physical activity, or eating too many foods that are high in cholesterol. During Zetia treatment, your doctor will likely recommend blood tests. joint pain *. But its possible that some side effects may continue to affect you for as long as youre taking the medication. Learn more about how grapefruit may interact with medications. Get emergency medical help if you have signs of an allergic reaction to Zetia: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Learn about the drugs dosage, forms, strengths. Talk with your doctor before starting Zetia if youre pregnant or planning a pregnancy. Taking Zetia with cholestyramine can decrease the amount of Zetia in your body. Other side effects not listed may also occur in some patients. However, animal studies dont always predict what will happen in humans. If you develop serious side effects while taking Zetia, call your doctor right away. Crestor contains the active drug rosuvastatin. They may have a preference for one version or the other. Porphyrias are rare, mainly genetic disorders that affect the body's ability to make hemoglobin. To reduce your symptoms in . 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